Thursday, April 2
| 2:45pm - 3:00pm | Welcome from CIS President and Program Chair Troy Torgerson, MD, PhD Allen Institute for Immunology |
| 3:00pm - 4:00pm | Plenary Session #1: Exceptional Abstracts 1 AMA PRA Category 1 Credits™ Oral Abstract Speakers: A Novel Monogenic Cause of Infantile-Onset IBD and Immune Dysregulation Mirrors the Murine Phenotype Natalia Chaimowitz, MD, PhD Baylor College of Medicine Three Copies of Four Interferon Receptor Genes Underlie Type I Interferonopathies in Down Syndrome Xiao-Fei Kong, MD, PhD St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University Translocation of Microbiota and Bacterial DNA are Related to Autoimmune/Inflammatory Complications and the Pathologic Interferon Signature in Common Variable Immunodeficiency Hsi-en Ho, MD Mount Sinai School of Medicine |
| 4:00pm - 5:30pm | Plenary Session #2: Immunology from the Perspective of Other Specialties: Gastroenterology 1.5 AMA PRA Category 1 Credits™ Speakers: Norovirus Pathogenesis, Treatment, and Prevention Robert Atmar, MD Baylor College of Medicine CVID and Inflammatory Gut Disease Silje F. Jørgensen Oslo University Hospital VEO-IBD Scott Snapper, MD, PhD Boston Children's Hospital |
| 5:30pm - 6:00pm | Break |
| 6:00pm - 7:00pm | Robert A. Good Lecture 1 AMA PRA Category 1 Credits™ Speaker: Tissue-Specific Immune Development Donna Farber, PhD Columbia Center for Translational Immunology |
| 7:00pm - 8:30pm | Early Career Immunologist Reception |
| 7:00 am - 8:00 am |
Continental Breakfast |
| 7:00 am - 8:00 am | Genomics & Genetics 101 *Separate Registration Required* 1 AMA PRA Category 1 Credits™ Speakers: Ivan Chinn, MD Baylor College of Medicine Tiphanie Vogel, MD, PhD Baylor College of Medicine |
| 7:00 am - 8:00 am | NIH Roundtable on Funding: DAIT/NIAID supported Investigator Initiated Clinical Trials (IICTs) Moderators: Frosso Voulgaropoulou, PhD Linda Griffith, MD Speakers:
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| 8:00 am - 9:15 am | Plenary Session#3: Managing the Return of Genomic Sequencing Results 1.25 AMA PRA Category 1 Credits™ Speakers: Elizabeth Varga, MS, CGC Nationwide Children's Hospital Magdalena Walkiewicz, PhD & Morgan Similuk, ScM, CGC National Institute of Allergy and Infectious Diseases, NIH Benjamin Berkman, JD, MPH Department of Bioethics, NIH |
| 9:15 am - 9:45 am | Morning Break |
| 9:45 am - 10:45 am | Plenary Session #4: Molecular Diagnostics for Primary Immunodeficiency 1 AMA PRA Category 1 Credits™ Speakers: High Throughput, Multiplex Functional Assessment of Genetic Variants Richard James, PhD Seattle Children's Research Institute Modeling Primary Immunodeficiencies in Zebrafish Anna Huttenlocher, PhD University of Wisconsin, Madison Oral Abstract Speaker: A Novel Immunodeficiency Disease Associated With a Congenital Disorder of Glycosylation: MAN2B2 Deficiency Luigi Notarangelo, MD Laboratory of Clinical Immunology and Microbiology, NIAID, NIH |
| 10:45 am - 11:30 am | Plenary Session #5: Tales from the VUServ .75 AMA PRA Category 1 Credits™ Moderator: Joshua Milner, MD, Columbia University Neil Romberg, MD, Children's Hospital of Philadelphia Panelists: Elizabeth Varga, MS, CGC Nationwide Children's Hospital Magdalena Walkiewicz, PhD National Institute of Allergy and Infectious Diseases, NIH Morgan Similuk, ScM, CGC National Institute of Allergy and Infectious Diseases, NIH |
| 11:30 am - 1:30 pm | Lunch and Exhibit Hall Open |
| 11:30 am - 12:30 pm | Mid-Career Luncheon: Bridging the Gap Between Learning and Leading Panelists:
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| 12:00 pm - 12:30 pm | Friday Lightning Posters in Exhibit Hall |
| 12:30 pm - 1:30 pm | Friday Poster Session |
| 1:30 pm - 3:50 pm | Plenary Session #6: Complement 2.25 AMA PRA Category 1 Credits™ Speakers: Review of Complement and Complement Testing Jordan Abbott, MA, MD National Jewish Health A Role for Complement in Protection Against Fungal Infection? Michail Lionakis, MD, ScD National Institute of Allergy and Infectious Diseases, NIH The Non-Canonical Role of Complement in Lymphocyte Maturation and Development Claudia Kemper, PhD National Heart, Lung, and Blood Institute, NIH The Role of Complement in Synaptic Pruning and Neurodegeneration Andrea Joan Tenner, PhD University of California, Irvine CD55 Deficiency -- Complement Pathway Defects in the Gut Ahmet Ozen Marmara University Oral Abstract Speaker: Daratumumab (Anti-CD38) For Treatment of Disseminated Nontuberculous Mycobacteria in a Patient with Anti-IFN-Γ Autoantibodies Sebastian Ochoa Gonzalez, MD National Institutes of Health |
| 3:50 pm - 4:30pm | Afternoon Break |
| 4:30 pm - 5:30pm | CIS Rose/Fahey Founders Lecture 1 AMA PRA Category 1 Credits™ Speaker: IL-1 and Related Inflammatory Cytokines Charles Dinarello, MD University of Colorado at Denver |
| 5:30 pm - 6:30 pm | Plenary #7: PID Year in Review 1 AMA PRA Category 1 Credits™ Speakers: Basic Science Manish Butte, MD, PhD University of California, Los Angeles Translational Immunology Jennifer Heimall, MD Children's Hospital of Philadelphia Clinical Immunology Kathleen Sullivan, MD, PhD Children's Hospital of Philadelphia |
| 7:00 pm - 8:30 pm | Women in Clinical Immunology Sciences Reception: Make the Change, Be the Change Speaker: Stephanie Donner |
| 7:00 am - 8:00 am | Breakfast |
| 7:00 am - 8:00 am | Flow 101 *Separate Registration Required* 1 AMA PRA Category 1 Credits™ Speakers: Roshini Abraham, PhD Nationwide Children's Hospital Atilla Kumanovics, MD Mayo Clinic |
| 8:00 am - 9:30 am | Plenary #8: Clinical Outcomes Research in PID 1.5 AMA PRA Category 1 Credits™ Speakers: Pain, Fatiuge, and Perceived Health in PIDD Joud Hajjar, MD, MS Baylor College of Medicine Oral Abstract Speaker: The Natural History of STAT3 GOF Syndrome – The Range of Clinical Manifestations and Treatment Options Lisa Forbes Satter, MD Baylor College of Medicine |
| 9:30 am - 10:00 am | Morning Break |
| 10:00 am - 11:30 am | Plenary #9: Metabolism, Immunity, and Cancer 1.5 AMA PRA Category 1 Credits™ Speakers: HAVCR2 (TIM3) Deficiency and Cancer Nada Jabado, MD, PhD McGill University IgG4 Related Disease, Diagnosis, and Treatment--Is There a Link to Malignancy Shiv Pillai, MD, PhD Massachusetts General Hospital Impact of Metabolic Changes on T-Cell Function in Health and Disease Naomi Taylor, MD, PhD National Institutes of Health Oral Abstract Speaker: Microbiome, Metagenomic and Metabolomic Signatures Distinguish Patients with Enteropathy Associated with Inherited CTLA4 Haploinsufficiency Emilia Falcone, MD, PhD, FRCPC Montreal Clinical Research Institute (IRCM) and Université de Montréal |
| 11:30 am - 2:00 pm | Lunch/Exhibit Hall Open |
| 11:30 am - 12:30 pm | Early Career Immunologist Lunch: How to Carve a Niche and Lead Speakers:
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| 12:30 pm - 1:00 pm | Saturday Lightning Poster in Exhibit Hall |
| 1:00 pm - 2:00 pm | Saturday Poster Viewing |
| 2:00 pm - 2:30 pm | Presidential Award Lecture .5 AMA PRA Category 1 Credits™ Speaker: Daniel Kastner, MD, PhD National Human Genome Research Institute |
| 2:30 pm - 3:00 pm | Plenary #10: Diversity in the Immunology Workforce .5 AMA PRA Category 1 Credits™ Speaker: Carla Davis, MD Texas Children's Hospital/Baylor College of Medicine |
| 3:00 pm - 3:30 pm | CIS Business Meeting |
| 3:30 pm - 4:00 pm | Afternoon Break |
| 4:00 pm - 5:00 pm | William Shearer Memorial Lecture 1 AMA PRA Category 1 Credits™ Speaker: Jean-Laurent Casanova, MD, PhD The Rockefeller University |
| 5:00 pm - 6:30pm | Plenary #11: Tales from the Listserv 1 AMA PRA Category 1 Credits™ Moderators: Eric Allenspach, MD, PhD University of Washington & Seattle Children's Hospital Elie Haddad, MD, PhD CHU Ste-Justine, University of Montreal Mikko Seppänen, MD, PhD Helsinki University Central Hospital Speaker: Mystery Case #1 Avni Joshi, MD, MS Mayo Clinic Mystery Case #2 Alica Chau, MD, MSE University of Washington Mystery Case #3 Jordan Abbott, MA, MD National Jewish Health |
| 6:30 pm - 8:00 pm | Closing Reception in Exhibit Hall |
| 8:00 pm - 9:30 pm | Talent Show to Benefit the CIS Foundation *Ticket Required* |
| 7:00 am - 8:00 am | Breakfast |
| 8:00 am - 10:30 am | Plenary #12: Hot New Defects in Primary Immunodeficiencies 2.5 AMA PRA Category 1 Credits™ Speakers: Helen Su, MD, PhD NIAID, NIH Christopher Duncan, MD, PhD Newcastle University Oral Abstract Speakers: Mosaic Gain-Of-Function Variants in TLR8 Lead to a Human X-Linked Primary Immunodeficiency with Both Features of Bone Marrow Failure and Autoimmunity Jahnavi Aluri, PhD Washington University in St. Louis PU.1 Haploinsufficiency Constrains Chromatin Accessibility and Arrests Human B-Cell Development Carole Le Coz, PhD Children's Hospital of Philadelphia Truncating Mutations in SAMD9L Cause an Early-Onset Immune-Dysregulatory Syndrome of Neutrophilic Panniculitis, Interstitial Lung Disease and Cytopenias Adriana Almeida de Jesus, MD, PhD Translational Autoinflammatory Disease Section, Laboratory of Clinical Immunology and Microbiology, NIAID, NIH |
Online Registration Closes
March 6
Housing Closes
March 10